Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 49674-16-0, name is 5-Amino-3-bromobenzonitrile, This compound has unique chemical properties. The synthetic route is as follows., Quality Control of 5-Amino-3-bromobenzonitrile
To a stirring solution of 103 mg (0.520 mmol) of 3-amino-5-bromobenzonitrile in 3 mL of pyridine was added 0.12 mL (1.27 mmol) Of Ac2O. The solution was stirred at r.t. for about 5.5 h and concentrated. Ethyl acetate was added, and the organic layer was washed with H2O and brine, dried over Na2SO4, filtered and concentrated. N-(3-bromo-5- cyanophenyl)acetamide was used for the next reaction without further purification.
According to the analysis of related databases, 49674-16-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; COMENTIS, INC.; PURDUE RESEARCH FOUNDATION; WO2009/42694; (2009); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts