Related Products of 50594-78-0, A common heterocyclic compound, 50594-78-0, name is 5-Fluoro-2-nitrobenzonitrile, molecular formula is C7H3FN2O2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
A mixture of 5-fluoro-2-nitrobenzonitrile (9.7Og, 58mmol) and 10% palladium on charcoal (Ig) in MeOH (20OmL) was stirred under an atmosphere of hydrogen for 5h. The mixture was filtered through a pad of celite and evaporated. The residue was triturated with Et2O-hexane EPO
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; JAMES BLACK FOUNDATION; WO2006/129120; (2006); A2;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts