Adding a certain compound to certain chemical reactions, such as: 6621-59-6, name is 6-Bromohexanenitrile, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 6621-59-6, Recommanded Product: 6-Bromohexanenitrile
General procedure: TBAF in 1M THF was added to a starting solution of alkyl-substituted triazole (8a-c) or non-substituted triazole (7a) in dried THF. The mixture was stirred for 24-48 h at 60 C, and the solution was cooled to room temperature. The mixture was poured into ethyl acetate and water and extracted twice with ethyl acetate. The combined organic layers were dried with Na2SO4, filtered and concentrated. The residue was purified by silica gel column chromatography (hexane/ethyl acetate) to yield the desired compound.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 6-Bromohexanenitrile, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Lee, Sun-Mi; Yoon, Kyoung Bin; Lee, Hyo Jeong; Kim, Jiwon; Chung, You Kyoung; Cho, Won-Jea; Mukai, Chisato; Choi, Sun; Kang, Keon Wook; Han, Sun-Young; Ko, Hyojin; Kim, Yong-Chul; Bioorganic and Medicinal Chemistry; vol. 24; 21; (2016); p. 5036 – 5046;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts