50846-36-1, name is 2-Amino-2-methylpropanenitrile hydrochloride, belongs to nitriles-buliding-blocks compound, is considered to be a conventional heterocyclic compound, which is widely used in drug synthesis. The chemical synthesis route is as follows. COA of Formula: C4H9ClN2
To a solution of Compound 20 (20 mg), 2-amino-2-methylpropanenitrile hydrochloride (9.32 mg, 0.077 mmol) and HATU (22.05 mg) in DMF (2 mL) was added iPr2NEt (0.027 mL). The mixture was stirred at room temperature for 4 hours. The product was isolated by preparative HPLC system
The synthetic route of 50846-36-1 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; BRISTOL-MYERS SQUIBB COMPANY; Wang, Tao; Eastman, Kyle J.; Zhang, Zhongxing; Parcella, Kyle E.; Yin, Zhiwei; Kadow, John F.; US2015/266886; (2015); A1;,
Nitrile – Wikipedia,
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