In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 134450-56-9 as follows. category: nitriles-buliding-blocks
1 mmol of the starting material CN-1-1, 3.0 mmol of potassium carbonate and 2.5 mmol of the starting material F-8-2, Was added to 10 mL of dimethylsulfoxide and heated at 150 C for 8 hours. After cooling to room temperature, 200 mL of water was added to the system to precipitate a solid which was purged and purified by column chromatography to give a solid.
According to the analysis of related databases, 134450-56-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Ruisheng Optoelectric Science And Technology (Changzhou) Co., Ltd.; Huang Da; Cao Chenhui; Xie Zaifeng; Ma Tengda; (39 pag.)CN107011243; (2017); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts