Adding a certain compound to certain chemical reactions, such as: 19295-57-9, name is 3-Hydroxy-2,2-dimethylpropanenitrile, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 19295-57-9, SDS of cas: 19295-57-9
770 g of 35% by weight of concentrated hydrochloric acid was added to the crude 2,2-dimethyl-3-hydroxypropanenitrile under heating and heated to 35 C for 3 hours. After the completion of the reaction, hydrochloric acid and water were distilled off to give 2,2-dimethyl- 3-hydroxypropionamide crude product 222g, purity 66.2%, the target product yield of this step about 84.9%.
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Reference:
Patent; Wanhua Chemical Group Co., Ltd.; Wang Peng; He Guangwen; Cui Qian; Cong Xin; Li Yuan; (6 pag.)CN107129435; (2017); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts