Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 50594-78-0, name is 5-Fluoro-2-nitrobenzonitrile, A new synthetic method of this compound is introduced below., Product Details of 50594-78-0
5-Fluoro-2-nitrobenzenecarbonitrile (1.02 equivalents) and N- methylpiperazine (1.0 equivalents) were dissolved in NMP. Triethylamine (2.1 equivalents) was added, and the resulting solution heated at 100 C for 1 hour. The solution was cooled to room temperature and poured into H20. A precipitate formed which was filtered to yield the desired product as a green solid. LC/MS M/Z 247.3 (MH+), Rt 1.46 minutes.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; CHIRON CORPORATION; WO2004/18419; (2004); A2;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts