In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 628-20-6 as follows. Recommanded Product: 628-20-6
General procedure: To a solution of 4-dimethylaminopyridine (2 g, 0.0163 mol) in 20 mL of toluene, was added the appropriate alkyl halide (1.1 eq) at room temperature. The mixture was placed in a closed vessel and exposed to ultrasound irradiation for 5 h at 80 C using a sonication bath. The completion of the reaction was marked by the separation of oil or a solid from the initially obtained clear and homogenous mixture of 4-dimethylaminopyridine and alkyl halide in toluene. The product was isolated by extraction or filtration to remove the unreacted starting materials and solvent. Subsequently, the pyridinium IL was washed with (3 × 20 mL) of ethyl acetate followed by drying under reduced pressure.
According to the analysis of related databases, 628-20-6, the application of this compound in the production field has become more and more popular.
Reference:
Article; Messali, Mouslim; Molecules; vol. 20; 8; (2015); p. 14936 – 14949;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts