Adding a certain compound to certain chemical reactions, such as: 5414-21-1, name is 5-Bromovaleronitrile, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 5414-21-1, name: 5-Bromovaleronitrile
EXAMPLE 1 5-{4-[2-(4-Pyridinyl)-ethenyl]-phenoxy}-valeronitrile To the solution of 1.16 g (50 mmol) sodium in 250 ml 2-propanol one adds 10.0 g (50 mmol) 4-[2-(4-pyridinyl)-ethenyl]-phenol, heats under reflux for 10 min, allows to cool, adds thereto 8.1 g (50 mmol) 5-bromovaleronitrile and heats to reflux for 16 h. One evaporates, mixes with water, extracts with dichloromethane, dries the extract, evaporates and triturates the residue with ether. One obtains 11.9 g of title compound (86% of theory) of the m.p. 85-87 C.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 5-Bromovaleronitrile, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Boehringer Mannheim GmbH; US5399575; (1995); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts