Reference of 1953-99-7, A common heterocyclic compound, 1953-99-7, name is 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile, molecular formula is C8Cl4N2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
3,4,5,6- tetrachloro phthalo nitrile 0.1 mol anddiethylmalonate 0.1 mol, and potassium carbonate 0.1 mol were stirred withdimethylformamide 60 g at 60 for3~4 hours. Afterthe reaction was complete, the reaction solution was cooled down atroom temperature. The reaction solution was added to water 250 g to crystallizeitself. Thecrystals were filtered under reduce pressure and were dispersedly filtered inthe mixed solution of methanol 50g and water 50g for 1 hour. The crystals were suction filteredand vacuum dried at 60 toobtain [formulaf] compound 30g.
The synthetic route of 1953-99-7 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Kyung-In Synthetic Corporation; Park, Soon Hyeon; Kim, Jeong Ki; Kim, Jeong Rok; Lee, Yun Ah; Lee, Do kyeong; Lee, Min Jeong; Lee, Hui Jae; (16 pag.)KR2016/7024; (2016); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts