Synthetic Route of 133116-83-3, The chemical industry reduces the impact on the environment during synthesis 133116-83-3, name is 2-Fluoro-6-(trifluoromethyl)benzonitrile, I believe this compound will play a more active role in future production and life.
Method 16 2-Amino-6-trifluoromethylbenzenecarbonitrile 2-Fluoro-6-trifluoromethylbenzenecarbonitrile was heated at 100 C. in a saturated solution of NH3 in EtOH overnight. The reaction mixture was concentrated and the residue was purified by column chromatography on silicagel (EtOAc/Hexanes 1:5), to obtain the title compound as a white solid. GC/MS m/z 186.1 (M+), Rt 10.1 minutes.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-Fluoro-6-(trifluoromethyl)benzonitrile, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Chiron Corporation; US2005/261307; (2005); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts