Simple exploration of 3-Oxobutanenitrile

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 2469-99-0.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 2469-99-0, name is 3-Oxobutanenitrile, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 3-Oxobutanenitrile

Step 3. 2-Benzyl-3-oxobutanenitrile To a solution of Na (1.17 g, 50.87 mmol) in EtOH (20 mL) was added 3-oxobutanenitrile (2.5 g, 30.09 mmol) and (bromomethyl)benzene (5 g, 29.23 mmol), and the reaction mixture was stirred for 2 hours at 80 C. The resulting mixture was concentrated in vacuo, diluted with water (200 mL), adjusted to pH 6 with HCl (3N), extracted with ethyl acetate (3*100 mL), dried over anhydrous magnesium and concentrated in vacuo to provide a residue, which was purified via silica gel column chromatography with 1.25% to 5% ethyl acetate in petroleum ether to afford 2-benzyl-3-oxobutanenitrile as a brown solid (2 g, 39%). LC/MS (ES, m/z):[M+H]+ 174.1

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 2469-99-0.

Reference:
Patent; BIOENERGENIX; US2012/277224; (2012); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts