Application of 118431-88-2, A common heterocyclic compound, 118431-88-2, name is 3-Cyclopropyl-3-oxopropanenitrile, molecular formula is C6H7NO, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
The compounds listed below may be prepared in manner similar to the method described above. COMPOUND 638: 1-[2-chloro-4-(methylsulphonyl)phenyl]-2-cyano-3-cyclopropylpropan-1,3-dione, m.p. 145 C., starting from 3-cyclopropyl-3-oxopropanonitrile and 2-chloro-4-(methylsulphonyl)benzoyl chloride.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Rhone-Poulenc Agriculture Limited; US5804532; (1998); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts