Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 63069-50-1, name is 4-Amino-3-fluorobenzonitrile, This compound has unique chemical properties. The synthetic route is as follows., Formula: C7H5FN2
To a mixture of 4-amino-3-fluorobenzonitrile 150 mg, triethylamine 0.38 mL, and THF 10 mL was added dropwise butyryl chloride 0.19 mL, and the resulting mixture was stilTed at room temperature for 1 hour. The reaction solution was filtered, and then concentrated under reduced pressure. To a mixture of the resulting residues and ethanol 10 mL was added dropwise a 50% aqueous hydroxylamine solution 0.22 mL, and the resulting mixture was stilTed at 80C for 2 hours. The reaction solution was concentrated under reduced pressure. To a mixture of the resulting residues and DMF 10 mL was added dropwise pyridine 0.22 mL at room temperature, and subsequently added dropwise trifluoroacetic anhydride 0.18 mL, and then the resulting mixture was stilTed at 100C for 2 hours. To the reaction solution was added water, and the precipitates were filtered, and the filtered substances were washed with water and hexane, and then dried under reduced pressure to give the Present compound 12 represented by the following formula 130 mg. 1HNMR (CDC13) oe: 8.59 (1H, t), 7.92-7.89 (1H, m), 7.86-7.82 (1H, m), 7.48 (1H, brs), 2.42 (2H, t), 1.83-1.74 (2H, m), 1.02 (3H, t)
According to the analysis of related databases, 63069-50-1, the application of this compound in the production field has become more and more popular.
Reference:
Patent; SUMITOMO CHEMICAL COMPANY, LIMITED; YAMAMOTO, Masaoki; ARIMORI, Sadayuki; (34 pag.)WO2018/56340; (2018); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts