Related Products of 658-99-1,Some common heterocyclic compound, 658-99-1, name is 2-(3,4-Difluorophenyl)acetonitrile, molecular formula is C8H5F2N, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
22.1.1 Synthesis of 3-cyano-3-(3,4-difluorophenyl)pentanedioic Acid Diethyl Ester Prepare by the method of Example 3.1.2 using 3,4-difluorophenylacetonitrile to give the title compound.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route 2-(3,4-Difluorophenyl)acetonitrile, its application will become more common.
Reference:
Patent; Maynard, George D.; Le, Tieu-Binh; US2001/34343; (2001); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts