Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 1009-35-4, name is 4-Fluoro-3-nitrobenzonitrile, A new synthetic method of this compound is introduced below., Recommanded Product: 1009-35-4
[0222] To a solution of 4-fluoro-3-nitrobenzonitrile (0.100 g, 0.600 mmol) and l-(2-chloro~6- fluorobenzyl)piperazine (0.102 g, 0.446 mmol) in ACN (1 mL) was added K2CO3 (0.185 g, 1.338 rnmol). The reaction mixture was heated to 80°C for 3 hours and then diluted with water (3 mL). Tlie liquid phase was decanted and tlie solid phase was washed with water and dried in a vacuum oven at 70°C for 4 hours to give the title compound, which was used without further purification.
The synthetic route of 1009-35-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; TAKEDA PHARMACEUTICAL COMPANY LIMITED; GREEN, Jason; HOPKINS, Maria; JONES, Benjamin; KIRYANOV, Andre A.; KUEHLER, Jon; MONENSCHEIN, Holger; MURPHY, Sean; NIXEY, Thomas; SUN, Huikai; (300 pag.)WO2018/183145; (2018); A1;,
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