Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 939-80-0, name is 4-Chloro-3-nitrobenzonitrile, This compound has unique chemical properties. The synthetic route is as follows., name: 4-Chloro-3-nitrobenzonitrile
General procedure: 0.5 mmol nitrobenzene, 4.0 mmol TBH (70%. aq. soln.), 40 mg Co-Ni/ Lignin catalyst and 10 mL Toluene were added in to an 80 mL autoclave. It was then exchanged with 4.0 MPa H2. The reaction was reacted at 160 C for 36 h under magnetic stirring. Subsequently, the autoclave was cooled to room temperature, and 70 mg biphenyl and 10 mL ethanol were added for quantitative analysis by GC-FID (Agilent 6890A). Purification Procedure: The crude products were subjected to silica gel column chromatography (60, 230-400 mesh supplied by Qingdao Haiyang Chemical and Special Silica Gel Co, Ltd). Eluting with ~75mL of Petroleum Ether, followed by 100:1 (Petroleum Ether:EtOAc).
According to the analysis of related databases, 939-80-0, the application of this compound in the production field has become more and more popular.
Reference:
Article; Pang, Shaofeng; Shi, Feng; Tetrahedron Letters; vol. 57; 52; (2016); p. 5872 – 5876;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts