These common heterocyclic compound, 1953-99-7, name is 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route. name: 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile
To a 100 mL flask4-Bis (?,? – dimethylbenzyl) -2-yloxy) -3,5,6-trichloro-phthalonitrile (0.5 g), 3,4,5,6-Tetrachlorophthalonitrile (0.85 g), 1,8-Diazabicycloundec-7-ene (0.7 g),1-pentanol (7 g) and zinc acetate (0.4 g) were added and stirred while heating to 140 ° C. After completion of the reaction, the mixture is concentrated and purified by column chromatography. The liquid obtained after purification is concentrated to obtain a solid. The crystallized solid was vacuum-dried to obtain a compound represented by the following formula (C-3).
The synthetic route of 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Samsung SDI Co., Ltd; Jeong Ui-su; Seo Hye-won; Shin Myeong-yeop; Han Gyu-seok; (40 pag.)KR2019/13136; (2019); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts