Adding a certain compound to certain chemical reactions, such as: 31643-49-9, name is 4-Nitrophthalonitrile, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 31643-49-9, Recommanded Product: 4-Nitrophthalonitrile
Under inert gas (N?), 4~Mtro~o~phth.ak>nitrile (9.2 g), phenol (5.0 g), .2CO3 (7.3 g) and DMSO (40 mL) were added into a flask, and were stirred and reacted at room temperature for 48 hrs., then heated to 60 C and reacted for 2 hrs. After cooled down, the reaction mixture was filtered and the resulted yellow solid was dried to obtain 11.6 g of Compound 1.
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Reference:
Patent; ZHEJIANG BETA PHARMA INCORPORATION; KANG, Xinshan; LONG, Wei; ZHANG, Jianxi; HU, Yunyan; WANG, Yinxiang; WO2013/13609; (2013); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts