In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 6330-25-2, name is 2-Cyano-N-methyl-acetamide belongs to nitriles-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Safety of 2-Cyano-N-methyl-acetamide
After 32.03 parts of phthalonitrile were added to 224.21 parts of formamide and stirred, 39.0 parts of sodium hydroxide was added and the mixture was stirred at 50 C. for 1 hour.320 parts of water and 25.75 parts of 2-cyano-N-methylacetamide were added, and the mixture was stirred at 50 C. for 2 hours. Next, 640 parts of 80% acetic acid and 36.82 parts of barbituric acid were added, and the mixture was stirred at 90 C. for 3 hours. After cooling to 80 C., the non-volatile components were filtered off with a Buchner funnel and washed with 3000 parts of water.
The synthetic route of 6330-25-2 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Toyo Ink Mfg. Co., Ltd.; Aikyo, Sumihiro; Nishida, Kazufumi; (40 pag.)JP2020/26503; (2020); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts