Application of 64248-62-0, The chemical industry reduces the impact on the environment during synthesis 64248-62-0, name is 3,4-Difluorobenzonitrile, I believe this compound will play a more active role in future production and life.
3-Fluoro-4-(4-formyl-phenoxy)-benzonitrile Stir a mixture of 4-hydroxy-benzaldehyde (50 g, 1.00 equiv, 409.4 mmol) and 3,4-difluoro-benzonitrile (56.96 g, 1.00 equiv) in DMA (750 mL) at 23 C. until completely dissolved. Add potassium carbonate (1.5 equiv, 84.88 g) and heat the mixture at 100 C. for 3 h. Cool to room temperature. Pour the reaction mixture over H2O-ice (1.5 L). Filter the solid over filter paper, wash the solid with water twice, and dry under reduced pressure to obtain Intermediate 1. (82.40 g, 83% yield). MS (APCI): (M+-1) 240.0
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 3,4-Difluorobenzonitrile, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Buezo, Nuria Diaz; Pedregal-Tercero, Concepcion; McKinzie, David Lee; Mitch, Charles Howard; US2009/186873; (2009); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts