Adding a certain compound to certain chemical reactions, such as: 29509-06-6, name is 4-Methyl-3-oxopentanenitrile, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 29509-06-6, Computed Properties of C6H9NO
A solution of 4-meroyl-3-oxorhoentanenitrile (Compound [CCLXJ) (8.8 g, 79.2 mmol, 1.00 equiv) and NH2NH2 H2O (80%, 7.5 g, 120 mmol, 1.50 equiv) in ethanol (300 mL) was heated to reflux for 1 h under nitrogen. After removed the solvent under vacuum, the residue was loaded onto a silica gel column with dichloromethane/methanol as an eluent to give Compound [CCLXIJ as a yellowish oil: LC-MS m/e 126 (M+H) +; 1H NMR (300 MHz, DMSO- d6) delta ppm 5.17 (s, 1H), 2.75 (septet, J = 6.9 Hz, 1H), 1.14 (d, J = 6.9 Hz, 6H).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Methyl-3-oxopentanenitrile, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; MERCK SHARP &; DOHME CORP.; BANYU PHARMACEUTICAL CO., LTD.; FAN, Weiming; HAXELL, Thomas, F. N.; JENKS, Matthew, G.; KAWANISHI, Nobuhiko; LEE, Shuliang; LIU, Hao; MALASKA, Michael, J.; MOORE, Joseph, A., III; OGINO, Yoshio; ONOZAKI, Yu; PANDI, Bharathi; PEEL, Michael, R.; SAKAMOTO, Toshihiro; SIU, Tony; WO2010/104933; (2010); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts