Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 194853-86-6, name is 4-Fluoro-2-(trifluoromethyl)benzonitrile, A new synthetic method of this compound is introduced below., Recommanded Product: 194853-86-6
3,3?-bicarbazole (0.50 g, 1.5 mmol), potassium carbonate (0.99 g, 7.2 mmol), 2-trifluoromethyl-4-fluorobenzonitrile (0.60 g, 3.3 mmol), DMSO 6 ml, 140 Heated at for 12h.Cool to room temperature and pour into 200ml of water to precipitate a large amount of solid and stir for 0.5h.A white solid was obtained by suction filtration and purified by column chromatography to obtain a white solid with a yield of 92%.
The synthetic route of 194853-86-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Nanjing Tech University; Tao Youtian; Cao Xudong; Hu Jia; Huang Wei; (9 pag.)CN105037247; (2019); B;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts