The important role of 3,4,5,6-Tetrafluorophthalonitrile

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 3,4,5,6-Tetrafluorophthalonitrile, and friends who are interested can also refer to it.

Adding a certain compound to certain chemical reactions, such as: 1835-65-0, name is 3,4,5,6-Tetrafluorophthalonitrile, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 1835-65-0, category: nitriles-buliding-blocks

EXAMPLE 45 Synthesis of Tetrafluoro-1,3-diiminobenz[f]isoindoline Anhydrous ammonia was slowly bubbled through a stirred mixture of tetrafluorophthalonitrile (2.0 g), 25percent sodium methoxide in methanol (2.3 ml), and dry 1-butanol (10 ml) for 20 minutes. With continued ammonia introduction, the mixture was refluxed for 1 hour. After the resultant had cooled, the solvent was removed under vacuum with a rotary evaporator. The residue was treated with ether (50 ml) and the product was collected by filtration, washed sequentially with water (10 ml), and ether (10 ml), vacuum dried and weighed (0.45 g).

At the same time, in my other blogs, there are other synthetic methods of this type of compound, 3,4,5,6-Tetrafluorophthalonitrile, and friends who are interested can also refer to it.

Reference:
Patent; Buechler, Kenneth F.; Noar, Joseph B.; Tadesse, Lema; US2002/61602; (2002); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts