Extracurricular laboratory: Synthetic route of C14H10N2O2

According to the analysis of related databases, 79463-77-7, the application of this compound in the production field has become more and more popular.

Related Products of 79463-77-7, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 79463-77-7 as follows.

A mixture of 3-aminobenzotrifluoride (15 g, 93 mmol) and diphenyl cyanocarbon-imidate (22.2 g, 93 mmol) was heated at reflux in THF (100 ml) for 20 h. The r.m. was then concentrated under reduced pressure. H2O was then added and the resulting solid was filtered and dried in vacuo, yielding 20.7 g of intermediate 35 (72%).

According to the analysis of related databases, 79463-77-7, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Van Brandt, Sven Franciscus Anna; De Cleyn, Michel Anna Jozef; Gijsen, Henricus Jacobus Maria; Berthelot, Didier Jean-Claude; Surkyn, Michel; US2012/295891; (2012); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts