Adding a certain compound to certain chemical reactions, such as: 3544-25-0, name is 2-(4-Aminophenyl)acetonitrile, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 3544-25-0, Application In Synthesis of 2-(4-Aminophenyl)acetonitrile
(i) 4-Hydrazinophenylacetonitrile A solution of sodium nitrite (1.9 g) in water (16 ml) was added dropwise to a suspension of 4-aminophenylacetonitrile (3.6 g) in concentrated hydrochloric acid (37 ml) so that the temperature did not exceed +2 C. The resulting mixture was stirred overnight (room temperature), the yellow solid collected, washed with cold ethanol (20 ml) and ether (50 ml), dried (vacuum) to give the title compound as a yellow solid. This material was used in the next step without further purification
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-(4-Aminophenyl)acetonitrile, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Glaxo Group Limited; US4650810; (1987); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts