Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 83101-12-6, name is 4-(3-Hydroxypropyl)benzonitrile, This compound has unique chemical properties. The synthetic route is as follows., Computed Properties of C10H11NO
5 Synthsis of 3-(4-Cyanophenyl)propyl Methanesulfonate A mixture of 3-(4-cyanophenyl)propanol (3.77 g, 23.4 mmol), methanesulfonylchloride (2.96 g, 25.8 mmol), triethylamine (2.60 g, 25.7 mmol) and ethyl acetate (100 ml) was stirred at room temperature for 30 minutes. Then the reaction mixture was diluted with ethyl acetate and successively washed with water and brine, dried over MgSO4 and concentrated in vacuo. The residue was chromatographed on silica gel (60 g) with hexane-ethyl acetate (1:1) to give 3-(4-cyanophenyl)propane methanesulfonate as a colorless oil (4.79 g, 86percent). 1H-NMR (200 MHz, CDCl3) delta: 7.61 (2H, d, J=8.4 Hz), 7.31 (2H, d, J=8.4 Hz), 4.24 (2H, t, J=6.2 Hz), 3.02 (3H, s), 2.83 (2H, t, J=7.8 Hz), 2.09 (2H, tt, J=7.8 and 6.2 Hz). IR (neat): 3028, 2941, 2227, 1608, 1506, 1351, 1172, 975, 929, 836, 815 cm-1.
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 83101-12-6.
Reference:
Patent; Takeda Chemical Industries, Ltd.; US6235731; (2001); B1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts