Electric Literature of 134450-56-9, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 134450-56-9, name is 4,5-Difluorophthalonitrile, This compound has unique chemical properties. The synthetic route is as follows.
Type (1-1) synthetic method of compound structure shown in the: lower range of the nitrogen, the 4,5-difluoro -1,2-dicyanobenzene is hydrogenated (5mmol), phenoxazine (18mmol), Pd2(dba)3(0.8mmol), NaOtBu (30mmol) and tBu3P·HBF4(0.8mmol) into 100 ml dimethyl formamide in the DMF 80 C temperature under stirring overnight. The 10 ml in cold water is added to the mixture the reaction quenching. After cooling to room temperature to be mixture, by vacuum filtration, then through the column chromatography purification product type (1-1), the product is dried in a vacuum. Yield: 69%.
The chemical industry reduces the impact on the environment during synthesis 4,5-Difluorophthalonitrile. I believe this compound will play a more active role in future production and life.
Reference:
Patent; Photoelectric Co. Ltd. Kunshan States; duan, lian; zhang, yun ge; liu, song; Zhao, lei; (18 pag.)CN105418533; (2016); A;,
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