Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 6136-93-2, name is 2,2-Diethoxyacetonitrile, A new synthetic method of this compound is introduced below., Computed Properties of C6H11NO2
EXAMPLE II PREPARATION OF 2-ETHYLIDENE-6-METHYL-CIS-3-HEPTENAL A solution of 5.40 g of isobutylacetylene in 50 ml of diethyl ether is treated with 30 ml of 2.2 N n-butyl-lithium in hexane at -20 C, and after several minutes the resulting solution is treated with 8.50 g of diethoxy-acetonitrile and then warmed solwly to room temperature. After about 1.5 hours the dark mixture is cooled and brought to a pH of about 2 with 10% sulfuric acid. The layers are then separated and the organic layer is washed successively with water and saturated aqueous sodium bicarbonate solution and then dried over sodium sulfate. Evaporation of the solvent provides 4.6 g of a dark oil, shown by IR and NMR to contain 1,1-diethoxy-6-methyl-3-heptyn-2-one.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; International Flavors & Fragrances Inc.; US4107217; (1978); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts