Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 23842-82-2, name is 2-Amino-5-methoxybenzonitrile, A new synthetic method of this compound is introduced below., Safety of 2-Amino-5-methoxybenzonitrile
The N-carbethoxy starting material is prepared in the following manner: A mixture of 5-methoxyanthranilonitrile (Bartlett, Dickel and Taylor, J.A.C.S. 80, 136 (1958), 2.25 g) and ethyl chloroformate (60 ml) is heated under reflux for 20 min. and then concentrated to dryness at reduced pressure. The residue is taken up in toluene (20 ml) hexane (50 ml) added and the precipitate collected, washed with hexane and air dried to afford the pure urethane, mp. 142-144.
The basis of chemical reaction formula synthesis, the synthesis route is composed of some specific reactions and combined according to certain logical thinking. We look forward to the emergence of more reaction modes in the future.
Reference:
Patent; Ciba-Geigy Corporation; US4713383; (1987); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts