Reference of 766-84-7, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 766-84-7 as follows.
General procedure: An equimolar mixture of 2-aminoethanol (1.0 mmol) and sulfur(1.0 mmol) was heated under solvent-free condition at 50C. Nitrile (1.0 mmol) was then added to reaction mixture and refluxed at 80C. The progress of the reaction was monitored through TLC (n-hexane: EtOAc, 8:2). After completion of the reaction, excess of water was added, and the product was filtered (for solid). Further chromatographic purification afforded pure product. All the compounds were characterizedby infrared (IR) and 1H NMR and 13C NMR spectroscopic data, as well as by comparison with data of reported compounds.
According to the analysis of related databases, 766-84-7, the application of this compound in the production field has become more and more popular.
Reference:
Article; Bansal, Shivani; Gupta, Poonam; Halve; Phosphorus, Sulfur and Silicon and the Related Elements; vol. 191; 7; (2016); p. 971 – 974;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts