Some tips on

Reference of 3544-25-0, The chemical industry reduces the impact on the environment during synthesis 3544-25-0, name is 2-(4-Aminophenyl)acetonitrile, I believe this compound will play a more active role in future production and life.

Example 52; 5-Cyano- 1 H-imidazole-2-carboxylic acid [2-(4 j4-dimethyl-cyclohex- 1 -enyl)-4-( 1 H-tetrazol-5 – ylmethyl)-phenyl] -amide; a) (4-Amino-3-bromo-phenyl)-acetonitrile; A solution of 4-aminophenylacetonitrile (1.45 g, 10.9 mmol) in acetonitrile (10 mL) at 00C was treated with NBS (1.95 g, 10.9 mmol) in acetonitrile (10 mL) dropwise via an addition funnel. The reaction was allowed to warm to room temperature and then concentrated in vacuo. The crude product was dissolved in EtOAc (50 mL), washed with saturated aqueous NaHCO3 (2 x 50 mL) and dried (Na2SO4). Removal of the solvent in vacuo afforded the title compound (2.12 g, 92%) as a reddish solid. Mass spectrum (ESI, m/z): Calcd. for C8H7BrN2, 210.9 (M+H), found 211.0.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-(4-Aminophenyl)acetonitrile, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; JANSSEN PHARMACEUTICA, N.V.; WO2007/123516; (2007); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts