Related Products of 332-25-2, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 332-25-2, name is 4-(Trifluoromethoxy)benzonitrile belongs to nitriles-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.
Hydroxylamine hydrochloride (2.8 g, 40 mmol),Sodium carbonate (2.7 g, 26 mmol) was dissolved in water (33 mL)4-Trifluoromethoxybenzonitrile (3.0 g, 16 mmol) andEthanol (17 mL) and heated at reflux for 6 hours.After cooling to room temperature, it was extracted with ethyl acetate (2 x 100 mL)The organic layers were combined, washed with saturated NaCl,Anhydrous Na2SO4 dried,The solvent was recovered to give 3.1 g of white powder in 89percent yield;
The synthetic route of 4-(Trifluoromethoxy)benzonitrile has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Zhejiang University; Sheng Rong; Hu Yongzhou; Cao Ji; Li Shan; Qiu Ni; Zhao Mengdan; Yang Bo; He Qiaojun; (33 pag.)CN106366078; (2017); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts