Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 20249-16-5, name is 3-Oxocyclobutanecarbonitrile, This compound has unique chemical properties. The synthetic route is as follows., Safety of 3-Oxocyclobutanecarbonitrile
a solution of 3-oxocyclobutane-1-carbonitrile (3.9 g, 41.01 mmol, 1.00 eq.) and 2-methylpropane-2-sulfinamide (4.97 g, 41.01 mmol, 1.00 eq.) in tetrahydrofuran (100 mL) was placed in a 250- mL 3-necked round-bottom flask and stirred for 16 hours at 70C. After cooled to room temperature, NaBH4 (780 mg, 20.53 mmol, 0.50 eq.) was added in portions and stirred for 30 mm at room temperature. The reaction was then quenched by the addition of water. The resulting solution was extracted with ethyl acetate and the organic layers combined. Theresulting mixture was washed with brine, dried over anhydrous sodium sulfate and concentrated under vacuum. This resulted in 7.5 g (9 1%) of N-(cis-3-cyanocyclobutyl)-2- methylpropane-2-sulfinamide as a yellow solid. LC-MS: (M+H) = 201.
According to the analysis of related databases, 20249-16-5, the application of this compound in the production field has become more and more popular.
Reference:
Patent; BASTOS Cecilia M.; MUNOZ Benito; TAIT Bradley; WO2015/196071; A1; (2015);,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts