Synthetic Route of 1953-99-7,Some common heterocyclic compound, 1953-99-7, name is 3,4,5,6-Tetrachlorobenzene-1,2-dicarbonitrile, molecular formula is C8Cl4N2, traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
To a 100 mL flask was added the solid (4- (biphenyl-2-ylamino) -3,5,6-trichlorophthalonitrile (1.0 g), 3,4,5,6-tetrachlorophthalonitrile (0.22 g), 1,8-Diazabicycloundec- -ene (1.0 g), and 1-pentanol (10 mL), and dissolve by heating. Then, zinc acetate (0.15 g) is added and refluxed with heating. After completion of the reaction, the solvent was removed, and the residue was purified by column chromatography. Dichloromethane is appropriately added to the obtained solid to dissolve the solid, and hexane is added to crystallize. At this time, the obtained solid is filtered and vacuum dried to obtain a compound represented by the following formula (C).
The synthetic route of 1953-99-7 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Samsung SDI Co.,Co.,Ltd; Kwon, Jae Young; Jung, Ju Ho; Lee, Yeon Soo; Lee, Jung Sun; Lee, Chang Ryul; (35 pag.)KR2016/22080; (2016); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts