Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 170572-49-3, name is 3-Fluoro-4-methylbenzonitrile, This compound has unique chemical properties. The synthetic route is as follows., Computed Properties of C8H6FN
To a heterogenous solution of 3-fluoro-4-methyl-benzonitrile (5 g, 37.0 mmol) in ethanol (125 mL) at 25C was added hydroxylamine hydrochloride (5.14 g, 74 mmol) and triethylamine (10.3 mL, 74 mmol). The reaction mixture was heated at 80C for 1 hour. After cooling to room temperature volatiles were removed under reduced pressure thus affording a white gum that was used in the next step without any purification. LC/MS (Method A) retention time = 0.25 minutes, 169.3 (M+H). (0416) NMR (400 MHz, DMSO-de) delta ppm: 7.44 (t, 2H), 7.32 (d, 1 H), 5.85 (brs, 2H), 4.50 (brs, 1 H) 2.24 (s, 3H). (0417) 9F NMR (400 MHz, DMSO-de) delta ppm: -1 14.46 (s).
Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 170572-49-3.
Reference:
Patent; SYNGENTA PARTICIPATIONS AG; HOFFMAN, Thomas, James; STIERLI, Daniel; BEAUDEGNIES, Renaud; POULIOT, Martin; HAAS, Ulrich, Johannes; (111 pag.)WO2018/219773; (2018); A1;,
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