Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 3759-28-2, name is 2-(Cyanomethyl)benzonitrile, A new synthetic method of this compound is introduced below., HPLC of Formula: C9H6N2
General procedure: Toa RB flask, 1-aryl/alkyl-3,3-bis-methylsulfanyl-propenone (1.0 mmol) and 2-cynomethyl-benzonitrile(1.0 mmol, 142.0 mg) was added. Then powderedKOH (2.0 mmol, 112.0 mg) and dry DMSO (5.0 mL) was added andreaction mixture was stirred for 2h at room temperature. Then reaction mixturewas quenched with ice-water and neutralized with 10% HCl and filtered. Crudewas purified by column chromatography using 15 % ethyl acetate in hexane as aneluent. All the compounds were characterized and reported earlier[1].
The synthetic route of 3759-28-2 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Rai, Reeta; Dutta, Roshan Kumar; Singh, Surjeet; Yadav, Dharmendra Kumar; Kumari, Seema; Singh, Harpreet; Gupta, Rinkoo Devi; Pratap, Ramendra; Bioorganic and Medicinal Chemistry Letters; vol. 28; 9; (2018); p. 1574 – 1580;,
Nitrile – Wikipedia,
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