Electric Literature of 75279-55-9, A common heterocyclic compound, 75279-55-9, name is 2-Chloro-6-fluorophenylacetonitrile, molecular formula is C8H5ClFN, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
Similar results are obtained when the above reaction is repeated using substituted-phenylacetonitriles. For example, when 1,4-dichlorobutene-2 is reacted with 6-chloro-2-fluorophenylacetonitrile or 4-nitrophenylacetonitrile in accordance with the above process 1-cyano-1-(6-chloro-2-fluorophenyl)-2-vinylcyclopropane and 1-cyano-1-(4-nitrophenyl)-2-vinylcyclopropane are respectively produced.
The synthetic route of 75279-55-9 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; National Distillers and Chemical Corporation; US4399076; (1983); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts