Discovery of 874-97-5

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 874-97-5.

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 874-97-5, name is 3-Cyanobenzyl alcohol, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 3-Cyanobenzyl alcohol

To a solution of 7-chloro-2,2-dimethyl-1-(methylsulfonyl)-2,3-dihydroimidazo[1,2-c]pyrimidin-5(1H)-one (200 mg, 0.720 mmol) and 3-(hydroxymethyl)benzonitrile (288 mg, 2.16 mmol) in N,N-dimethylformamide (DMF) (3.5 mL) was added K2CO3 (299 mg, 2.16 mmol). The reaction mixture was sealed in a microwave vial and irradiated with a microwave using initial normal to 100 C. for 1 h. Purification via mass-directed auto-preparation afforded the title product as a white solid. LCMS (ESI): m/z 297 [M+H]+; 2.24 min (ret time)

Chemical properties determine the actual use. Each compound has specific chemical properties and uses. We look forward to more synthetic routes in the future to expand reaction routes of 874-97-5.

Reference:
Patent; GlaxoSmithKline Intellectual Property Development Limited; WAN, Zehong; Sang, Yingxia; Zhang, Qing; US2014/213599; (2014); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts