Analyzing the synthesis route of C7H5N3O2

According to the analysis of related databases, 6393-40-4, the application of this compound in the production field has become more and more popular.

Related Products of 6393-40-4, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 6393-40-4 as follows.

1g (6.1mmol) 4-Amino-3-nitrobenzonitrile was dissolved in 50ml ethanol and was subjected to hydrogenation using 35 psi of H2 and 10% Pd.C until the end of H2 uptake. The catalyst was filtered on a bed of Celite, washed with ethanol and concentrated in vacuo. Powder residue was used for the subsequent steps without crystallization. Yield: 88% (0.72g). Mp: 144-146C.14

According to the analysis of related databases, 6393-40-4, the application of this compound in the production field has become more and more popular.

Reference:
Article; Karaaslan, Cigdem; Kaiser, Marcel; Brun, Reto; Goeker, Hakan; Bioorganic and Medicinal Chemistry; vol. 24; 18; (2016); p. 4038 – 4044;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts