Simple exploration of 243128-37-2

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Fluoro-3-methoxybenzonitrile, other downstream synthetic routes, hurry up and to see.

Reference of 243128-37-2, In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 243128-37-2, name is 4-Fluoro-3-methoxybenzonitrile belongs to nitriles-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below.

4.1.1. Synthesis of the Compounds 4 from Scheme 1 (Benzonitrile Derivatives)Synthesis of 4-morpholino-3-methoxy-benzonitrile (4.3) (for Examples 10, 70)6.7 mL (75 mmol) morpholine was stirred into 50 ml dimethylsulphoxide together with 20 g (141 mmol) potassium carbonate and 10.0 g (66 mmol) 4-fluoro-3-methoxy-benzonitrile for 8 h at 100 C. 500 ml ice water was added to the reaction mixture and the precipitate formed was filtered off and dried.Yield: 11.2 g (51 mmol=78% of theory)Analysis: HPLC-MS (method D): Rt: 1.36 min, (M+H)+: 219

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 4-Fluoro-3-methoxybenzonitrile, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; US2011/201608; (2011); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts