Adding a certain compound to certain chemical reactions, such as: 2973-50-4, name is 2-(2-Aminophenyl)acetonitrile, belongs to nitriles-buliding-blocks compound, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2973-50-4, category: nitriles-buliding-blocks
Adding the reactor 100mmol O-aminophenyl acetonitrile, 105mmol NBS and 100g polyethylene glycol 400, the reaction under stirring at room temperature for 2 hours. After the reaction, the mixture into ethyl acetate, saturated salt water for washing, the aqueous layer after extraction with ethyl acetate, combined with the organic layer (the washing of the organic layer and extraction of the organic layer), using anhydrous Na2SO4drying, negative-pressure evaporation to remove the solvent, the residue is column chromatography (petroleum ether/ethyl acetate, two volume ratio of 2:1) purification, to obtain the product 2-amino-5-brombenethane
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 2-(2-Aminophenyl)acetonitrile, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Wenzhou University; Chen, Jiuxi; Yu, Shuling; Cheng, Tianxing; Hu, Kun; Qi, Linjun; Liu, Miaochang; Wu, Huayue; (13 pag.)CN105884673; (2016); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts