Electric Literature of 873-74-5, These common heterocyclic compound, 873-74-5, name is 4-Aminobenzonitrile, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc, below Introduce a new synthetic route.
General procedure: All acyl chloride solutions were freshly prepared in acetonitrile (ACN) at 1 mg/mL. All amine solutions were freshly prepared in water (H2O) at 1mg/mL. A portion of each acyl chloride solution was mixed with an amine solution with an equal volume and the mixture was allowed to stand for about 10 min. Each mixture was diluted with ACN 10-fold for analysis.
The synthetic route of 873-74-5 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Zu, Chengli; Mukhopadhyay, Sukrit; Hanley, Patrick S.; Xia, Shijing; Bell, Bruce M.; Grigg, David; Gilbert, Jeffrey R.; O?Brien, John P.; Journal of the American Society for Mass Spectrometry; vol. 27; 5; (2016); p. 917 – 926;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts