Related Products of 1835-65-0, In the chemical reaction process, reaction time, type of solvent, can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product. An updated downstream synthesis route of 1835-65-0 as follows.
Nickel complexes 3?6. A mixture of 1.00 g (3.2 mmol) of nitrile 1, 0.64 g (3.2 mmol) of nitrile 2, and 0.50 g (2.0 mmol) of nickel(II) acetate tetrahydrate was stirred during 1 h at 210 °C. After cooling the reaction mixture, it was dissolved in 50 mL of dichloromethane and filtered through a 5 cm layer of type II alumina. The solvent was distilled off, and the residue was purified by column chromatography on Kieselgel 60 silica gel (Merck). First, complexes 3 and 4 were isolated using dichloromethane as eluent, and then complexes 5 and 6 were isolated using a 95 : 5 (v/v) mixture of dichloromethane and ethanol as eluent.
According to the analysis of related databases, 1835-65-0, the application of this compound in the production field has become more and more popular.
Reference:
Article; Koptyaev; Galanin; Shaposhnikov; Russian Journal of General Chemistry; vol. 86; 4; (2016); p. 854 – 858; Zh. Obshch. Khim.; vol. 86; 4; (2016); p. 667 – 671,5;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts