Reference of 3100-67-2, The chemical industry reduces the impact on the environment during synthesis 3100-67-2, name is 1-Amino-2-naphthonitrile, I believe this compound will play a more active role in future production and life.
The mixture was stirred into 200 mL of tetrahydrofuran and <9-a>, obtained from scheme 21, 25.0 g (149 mmol), phenyl magnesium bromide (3.0 M in Et2O) 87.4 mL (297 mmol) was added dropwise at 0 C and refluxed for about one hour. Ethyl chloroformate 19.4 g (179 mmol) was added dropwise and it was refluxed for about 1 hour. Then aqueous solution of ammonium chloride was added and then washed with water and heptane to give <9-b> 32.4 g (80% yield).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles, 1-Amino-2-naphthonitrile, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; SFC Co. Ltd.,; Yoo, Se Jin; Lee, Se Jin; (64 pag.)KR101554545; (2015); B1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts