Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 395675-23-7, name is 2-Chloro-5-fluorophenylacetonitrile, This compound has unique chemical properties. The synthetic route is as follows., SDS of cas: 395675-23-7
In step 1 Manufactured 2-(2-Chloro-5-fluorophenyl)acetonitrile (5.000 g, 29.485 mmol) and sodium hydride (60.00%, 2.948 g, 73.712 mmol) in N,N-dimethylformamide (40 mL) at 0 C and stirred for 30 min, to this mixture 1,3-dibromopropane (3.006 mL, 29.485 mmol) was added and this mixture was further stirred at room temperature for 18 hours. The reaction mixture was poured into water and extracted with dichloromethane. The organic layer was washed with a saturated aqueous sodium chloride solution, and water was removed with anhydrous magnesium sulfate, followed by filtration and concentration under reduced pressure. The concentrate was purified by column chromatography (SiO2, 80 g cartridge; ethyl acetate / hexane = 0% to 30%) and concentrated to give the title compound (2.271 g, 36.7%) as a white solid.
According to the analysis of related databases, 395675-23-7, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Chong Kun Dang Co., Ltd.; Kim, Yoon Tae; Lee, Chang Sik; Oh, Jung Taek; Song, Hey Sung; Choe, Jin; Lee, Jae Young; (210 pag.)KR2017/43091; (2017); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts