Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 66389-80-8, name is tert-Butyl 4-cyanobenzylcarbamate, A new synthetic method of this compound is introduced below., Recommanded Product: 66389-80-8
c) N-Boc-4-aminomethyl-N-hydroxy-benzamidine; To a solution of N-Boc-4-aminoethylbenzonitrile (14g; 60mmol) in THF (500ml) is added at 50C a solution of hydroxy Ia mine in water (1/1 ; 80ml; 1.8 mol). The reaction mixture is then stirred at room temperature for 16 hours. The reaction mixture is diluted with water and THF is removed under vacuo. The resulting precipitate is collected by filtration and dried. Pure title compound is obtained by recrystallization from diethylether.
The synthetic route of 66389-80-8 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; NOVARTIS AG; WO2008/37476; (2008); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts