Researchers who often do experiments know that organic synthesis is a process of preparing more complex target molecules from simple raw materials through one or more chemical reactions. Generally, it requires fewer steps, and cheap raw materials. 64113-86-6, name is 5-Methyl-2-nitrobenzonitrile, A new synthetic method of this compound is introduced below., Recommanded Product: 5-Methyl-2-nitrobenzonitrile
In a 1.0 L round bottomed flask, 12.375 g of the above nitrile and 12.30 grams of methyl-4-formylbenzoate were dissolved in 500 mL MeOH and 20.25 mL NaOMe was added. The reaction is allowed to stir for 96 hours, acidified with TFA to pH 4.0, chilled for 1 hour, filtered and washed with MeOH. Yield, 7.0 g; mp 266-269 C.; MS (FAB), (C17 H12 N2 O4), calcd, 308; found 309 (MH+).
The synthetic route of 64113-86-6 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Nair, Madhavan G.; US2010/260825; (2010); A1;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts