Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 19295-57-9, name is 3-Hydroxy-2,2-dimethylpropanenitrile, This compound has unique chemical properties. The synthetic route is as follows., Recommanded Product: 19295-57-9
To a solution of 3-hydroxy-2,2-dimethylpropanenitrile (0.5 g) in dichloromethane (8 ml_) and pyridine (1 .5 ml_) is added at 0C p-toluene-sulfonylchloride (1 .0 g) in portions. The mixture is stirred for 12 hours at room temperature, diluted with diethylether and washed with 1 M aqueous HCI solution and brine. After drying (MgSO4) the solvent is evaporated and the residue is chromatographed on silica gel (petrole ether/ethyl acetate 90:10?50:50) to give the title compound. Yield: 770 mg; Mass spectrum (ESI+): m/z = 254 [M+H]+.
According to the analysis of related databases, 19295-57-9, the application of this compound in the production field has become more and more popular.
Reference:
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; ECKHARDT, Matthias; FRATTINI, Sara; HAMPRECHT, Dieter; HIMMELSBACH, Frank; LANGKOPF, Elke; LINGARD, Iain; PETERS, Stefan; WAGNER, Holger; WO2013/144097; (2013); A1;,
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