In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 80517-21-1, name is 4-Fluoro-2-nitrobenzonitrile belongs to nitriles-buliding-blocks compound, it is a common compound, a new synthetic route is introduced below. Product Details of 80517-21-1
To the reactor was added 470 g of 2-nitro-4-fluorobenzonitrile and 3000 mL of DMF.Stir,The reaction temperature was controlled to be 60 to 90 C.190 g of sodium methoxide was added in portions, and the reaction was continued for a while after the addition was completed.GC tracking,Until the reaction is completed, the ice water is separated and filtered, and 478 g of solid 2-nitro-4-methoxybenzonitrile is obtained, and the content is more than 98%.The yield was 94.9%.
The synthetic route of 80517-21-1 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; Changzhou University; Chen Xingquan; Dong Yanmin; (6 pag.)CN109553534; (2019); A;,
Nitrile – Wikipedia,
Nitriles – Chemistry LibreTexts